The identity of the most recent fatality has yet to be released.
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The incident is the third confirmed traffic-related pedestrian fatality of 2020 already, according to SFPD.
Meanwhile, there have already been several traffic-related pedestrian injuries this year.
At least four other pedestrians were struck by drivers in one week.
A man in his 20s was struck by a driver early Sunday morning where the city’s high-injury network meets a state highway.
Another collision happened over the weekend when a driver struck a pedestrian near Golden Gate Park.
Jesus Ocampo is the 17th pedestrian or cyclist to die in San Francisco in 2019 thus far.
In just two days, drivers fatally struck one pedestrian and left another with a brain injury.
Traffic fatalities this year have SFMTA speeding up safety projects but advocates warn they can only go so far without proper enforcement.